Ozanimod for the treatment of relapsing remitting multiple sclerosis

  title={Ozanimod for the treatment of relapsing remitting multiple sclerosis},
  author={L. Rasche and F. Paul},
  journal={Expert Opinion on Pharmacotherapy},
  pages={2073 - 2086}
  • L. Rasche, F. Paul
  • Published 2018
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • ABSTRACT Introduction: Ozanimod is a selective sphingosine 1-phosphate receptor 1 and 5 modulator under development by Celgene, for the treatment of relapsing remitting multiple sclerosis. Extensive clinical experience has become available for the related compound fingolimod, favoring the sphingosine 1-phosphate therapeutic concept. Off-target effects have been attributed to its low receptor specificity and have prompted the development of next generation sphingosine 1-phosphate receptor… CONTINUE READING
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