Ozagrel attenuates early streptozotocin-induced constriction of arterioles in the mouse retina.

@article{Wright2008OzagrelAE,
  title={Ozagrel attenuates early streptozotocin-induced constriction of arterioles in the mouse retina.},
  author={William S. Wright and Norman R. Harris},
  journal={Experimental eye research},
  year={2008},
  volume={86 3},
  pages={528-36}
}
Retinal blood flow in human diabetics has been reported to follow a biphasic time course in which an initial period of reduced flow and ischemia is often followed by a hyperemic and angiogenic phase in which flow can exceed normal levels. The purpose of the present study is to investigate the mechanisms of the initial decrease in flow, since early interventions could provide the most effective treatment strategies. C57BL/6 mice were injected with streptozotocin (STZ) at 12 weeks of age and… CONTINUE READING
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