Oxytocinergic and serotonergic systems involvement in sodium intake regulation: satiety or hypertonicity markers?

@article{Godino2007OxytocinergicAS,
  title={Oxytocinergic and serotonergic systems involvement in sodium intake regulation: satiety or hypertonicity markers?},
  author={Andrea Godino and Laurival Ant{\^o}nio De Luca and Jose Antunes-Rodrigues and L Vivas},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2007},
  volume={293 3},
  pages={R1027-36}
}
Previous studies demonstrated the inhibitory participation of serotonergic (5-HT) and oxytocinergic (OT) neurons on sodium appetite induced by peritoneal dialysis (PD) in rats. The activity of 5-HT neurons increases after PD-induced 2% NaCl intake and decreases after sodium depletion; however, the activity of the OT neurons appears only after PD-induced 2% NaCl intake. To discriminate whether the differential activations of the 5-HT and OT neurons in this model are a consequence of the sodium… CONTINUE READING

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