Oxytocin receptor is expressed in the penis and mediates an estrogen-dependent smooth muscle contractility.

@article{Vignozzi2004OxytocinRI,
  title={Oxytocin receptor is expressed in the penis and mediates an estrogen-dependent smooth muscle contractility.},
  author={Linda 4 Vignozzi and Sandra Filippi and Michaela Luconi and Annamaria Morelli and Rosa Mancina and Mirca Marini and Gabriella Barbara Vannelli and Simone Granchi and C. James Orlando and Stefania Gelmini and Fabrizio Ledda and G. Cantelu Forti and Mario Maggi},
  journal={Endocrinology},
  year={2004},
  volume={145 4},
  pages={
          1823-34
        }
}
Oxytocin (OT) is released by the posterior pituitary during male orgasm and is supposed to participate in the ejaculatory process. We now report evidence demonstrating the presence of an OT receptor gene (real-time RT-PCR and Northern blot) and protein (immunohistochemistry, Western blot, and binding studies) expression in the rabbit and human corpus cavernosum (CC) and its possible involvement in postorgasmic penile detumescence. OT receptor is expressed in the penis at a concentration similar… CONTINUE READING

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