Oxytocin opposes effects of bacterial endotoxin on ER-stress signaling in Caco2BB gut cells.

@article{Klein2016OxytocinOE,
  title={Oxytocin opposes effects of bacterial endotoxin on ER-stress signaling in Caco2BB gut cells.},
  author={Benjamin Y. Klein and Hadassah Tamir and David L. Hirschberg and Robert J. Ludwig and Sara B. Glickstein and Michael M. Myers and Martha G Welch},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1860 2},
  pages={
          402-11
        }
}
BACKGROUND The neuropeptide neuromodulator and hormone oxytocin (OT) activates signaling pathways involved in mRNA translation in response to endoplasmic reticulum stress and reduces inflammation associated with experimental colitis in rats. The anti-inflammatory effects of OT may serve a vital role in the development, survival and function of newborn-type enterocytes during microbial gut colonization, which coincides with the milk suckling period when OT receptor expression peaks in the gut… CONTINUE READING
1
Twitter Mention

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Colostrum oxytocin modulates cellular stress response, inflammation, and autophagy markers in newborn rat gut villi.

  • Biochemical and biophysical research communications
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND & RESULTS

Enteric serotonin and oxytocin: endogenous regulation of severity in a murine model of necrotizing enterocolitis.

  • American journal of physiology. Gastrointestinal and liver physiology
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

Regulation of the macrophage oxytocin receptor in response to inflammation.

  • American journal of physiology. Endocrinology and metabolism
  • 2017
VIEW 3 EXCERPTS
CITES BACKGROUND & RESULTS

Approaches Mediating Oxytocin Regulation of the Immune System

  • Front. Immunol.
  • 2016
VIEW 3 EXCERPTS
CITES BACKGROUND