Oxytocin mediates social neuroprotection after cerebral ischemia.

  title={Oxytocin mediates social neuroprotection after cerebral ischemia.},
  author={Kate E Karelina and Kathleen A. Stuller and Brant Jarrett and Ning Zhang and Jackie Wells and Greg J. Norman and A Courtney Devries},
  volume={42 12},
BACKGROUND AND PURPOSE The reduced incidence, morbidity, and mortality of stroke among humans with strong social support have been well-documented; however, the mechanisms underlying these socially mediated phenomena remain unknown, but may involve oxytocin (OT), a hormone that modulates some aspects of social behavior in humans and other animals. METHODS In the present study, adult male mice were socially isolated (housed individually) or socially paired (housed with an ovariectomized female… CONTINUE READING
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