Oxytocin inhibits head and neck squamous cell carcinoma cell migration by early growth response-1 upregulation.

@article{Kim2017OxytocinIH,
  title={Oxytocin inhibits head and neck squamous cell carcinoma cell migration by early growth response-1 upregulation.},
  author={Jinkyung Kim and Sung-Min Kang and Heon-Jin Lee and So-young Choi and Su-Hyung Hong},
  journal={Anti-cancer drugs},
  year={2017},
  volume={28 6},
  pages={613-622}
}
The effect of oxytocin (OXT) on cancer invasion is controversial. Few studies have examined the effect of early growth response-1 (EGR1) on the invasion of head and neck squamous cell carcinoma (HNSCC). Here, we evaluated how EGR1 affects HNSCC cell migration through the molecular mechanism of OXT in exerting anti-invasion activity. Matrigel invasion and wound-healing assays were used to measure the in-vitro cell migration. The molecular mechanism of OXT was assessed by knockdown or… CONTINUE READING
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