Oxytocin induces social communication by activating arginine-vasopressin V1a receptors and not oxytocin receptors.

@article{Song2014OxytocinIS,
  title={Oxytocin induces social communication by activating arginine-vasopressin V1a receptors and not oxytocin receptors.},
  author={Zhimin Song and Katharine E. McCann and John K McNeill and Tony E Larkin and Kim L Huhman and H Elliott Albers},
  journal={Psychoneuroendocrinology},
  year={2014},
  volume={50},
  pages={14-9}
}
Arginine-vasopressin (AVP) and oxytocin (OT) and their receptors are very similar in structure. As a result, at least some of the effects of these peptides may be the result of crosstalk between their canonical receptors. The present study investigated this hypothesis by determining whether the induction of flank marking, a form of social communication in Syrian hamsters, by OT is mediated by the OT receptor or the AVP V1a receptor. Intracerebroventricular (ICV) injections of OT or AVP induced… CONTINUE READING
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