Oxytocin increases amygdala reactivity to threatening scenes in females

  title={Oxytocin increases amygdala reactivity to threatening scenes in females},
  author={Alexander Lischke and M. Gamer and C. Berger and A. Grossmann and G. Domes},
  • Alexander Lischke, M. Gamer, +2 authors G. Domes
  • Published 2012
  • Psychology, Medicine
  • Psychoneuroendocrinology
  • The neuropeptide oxytocin (OT) is well known for its profound effects on social behavior, which appear to be mediated by an OT-dependent modulation of amygdala activity in the context of social stimuli. In humans, OT decreases amygdala reactivity to threatening faces in males, but enhances amygdala reactivity to similar faces in females, suggesting sex-specific differences in OT-dependent threat-processing. To further explore whether OT generally enhances amygdala-dependent threat-processing in… CONTINUE READING
    168 Citations

    Paper Mentions

    Positive results in preclinical and clinical studies in adults and infants with Prader-Willi syndrome lead investigators to set up a new study in children with Prader-Willi syndrome. The… Expand
    ConditionsPrader-Willi Syndrome
    The objective of this study is to collect data on tolerance and effects of early treatment with oxytocin in children with Prader Willi Syndrome aged from 3 to 4 years and to compare… Expand
    ConditionsPrader-Willi Syndrome
    InterventionDrug, Other
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