Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats.

@article{Sabihi2014OxytocinIT,
  title={Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats.},
  author={Sara Sabihi and Nicole E. Durosko and Shirley M. Dong and Benedetta Leuner},
  journal={Psychoneuroendocrinology},
  year={2014},
  volume={45},
  pages={31-42}
}
The neuropeptide oxytocin (OT) is anxiolytic in rodents and humans. However, the specific brain regions where OT acts to regulate anxiety requires further investigation. The medial prefrontal cortex (mPFC) has been shown to play a role in the modulation of anxiety-related behavior. In addition, the mPFC contains OT-sensitive neurons, expresses OT receptors, and receives long range axonal projections from OT-producing neurons in the hypothalamus, suggesting that the mPFC may be a target where OT… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…