Oxytocin in Brattleboro rats: increased synthesis is contrasted by blunted intrahypothalamic release from supraoptic nucleus neurones.

@article{Zelena2013OxytocinIB,
  title={Oxytocin in Brattleboro rats: increased synthesis is contrasted by blunted intrahypothalamic release from supraoptic nucleus neurones.},
  author={D{\'o}ra Zelena and Ott{\'o} Pint{\'e}r and Kristina Langnaese and K. -D. Richter and Rainer Landgraf and G{\'a}bor B. Makara and Mario Engelmann},
  journal={Journal of neuroendocrinology},
  year={2013},
  volume={25 8},
  pages={711-8}
}
Adult male Brattleboro rats were used to investigate the impact of the congenital absence of vasopressin on the release pattern of oxytocin (OXT) within the hypothalamic supraoptic nucleus (SON) in response to a 10-min forced swimming session and osmotic stimulation. Both immunohistochemical and in situ hybridisation data suggest that vasopressin-deficient animals have more oxytocin-synthesising neurones in the SON than homozygous wild-type controls. Unexpectedly, both forced swimming and… CONTINUE READING