Oxytocin exerts protective effects on in vitro myocardial injury induced by ischemia and reperfusion.

  title={Oxytocin exerts protective effects on in vitro myocardial injury induced by ischemia and reperfusion.},
  author={M{\'a}ria Ondrejc{\'a}kov{\'a} and T{\'a}ňa Ravingerov{\'a} and Jan Bakos and Dezider Pancza and Daniela Jezova},
  journal={Canadian journal of physiology and pharmacology},
  volume={87 2},
Among the cardiovascular pathologies, ischemic heart disease is a serious medical problem that can result in cardiac injury and (or) heart failure. The aim of the present study was to test the hypothesis that neuropeptide oxytocin induces cardioprotective effects on ischemia-reperfusion-induced myocardial damage. The functional parameters of isolated Langendorff-perfused rat hearts were recorded before and after global 25 min ischemia and subsequent reperfusion. The infarct size was determined… 

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