Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex.

  title={Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex.},
  author={Chandra Sekhar Sripada and K. Luan Phan and Izelle Labuschagne and Robert Welsh and Pradeep J. Nathan and Amanda G. Wood},
  journal={The international journal of neuropsychopharmacology},
  volume={16 2},
The neuropeptide oxytocin (OXT) plays an important role in complex socio-affective behaviours such as affiliation, attachment, stress and anxiety. Previous studies have focused on the amygdala as an important target of OXT's effects. However, the effects of OXT on connectivity of the amygdala with cortical regions such as medial frontal cortex, an important mediator of social cognition and emotion regulation, remain unexplored. In a randomized, double-blind, cross-over design, 15 volunteers… CONTINUE READING


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