Oxytocin, Functions, Uses and Abuses: A Brief Review

  title={Oxytocin, Functions, Uses and Abuses: A Brief Review},
  author={Nafis Ibni Assad and Anand Kumar Pandey and L. M. Sharma},
  journal={Theriogenology Insight - An International Journal of Reproduction in all Animals},
  • N. AssadA. PandeyL. Sharma
  • Published 2016
  • Biology
  • Theriogenology Insight - An International Journal of Reproduction in all Animals
Oxytocin a peptide hormone has the distinction of being the first among the peptide hormones to be sequenced and biochemically synthesized. Oxytocin is secreted from neural as well as non-neural sources inside the body. Among the neural sources supra-optic and paraventricular nuclei of the brain are major sources of secretion, the arcuate nucleus being a minor source. There are many non-neural sources from which synthesis of Oxytocin has been reported. The important ones include interstitial… 

Oxytocin-functions: an overview

Oxytocin is known to be the 1st polypeptide hormone that has been sequenced and synthesized biochemically and is synthesized in the magnocellular neurosecretory cell bodies of both supraoptic and paraventricular hypothalamic nuclei and is stored in hypothalamo-hypophyseal tract until it is released into the blood.

The Role of Oxytocin in Domestic Animal’s Maternal Care: Parturition, Bonding, and Lactation

The role of OXT and the neurophysiologic regulation of this hormone during parturition, how it can promote or impair maternal behavior and bonding, and its importance in lactation in domestic animals is analyzed.

Oxytocin; Effects on Milk Production

Regular use of OT has many harmful effects on the animals and the human beings that used milk of OT used animals, so it should be sale on the veterinarian prescription and properly guide the farmers about OT.

Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses

It is convenient to know oxytocin’s different effects as well as the adequate doses and the proper moment to administrate it, as it can reduce labor duration, but it can also increase dystocia.

Oxytocin and Related Peptide Hormones: Candidate Anti-Inflammatory Therapy in Early Stages of Sepsis

Possible links between oxytocin and related octapeptide hormones and sepsis-related modulation of pro-inflammatory and anti-inflammatory activities are explored.

Benefit of oxytocin released by cervix stimulation in Mexican Holstein cattle

Investigation in Holstein cattle from the northwestern arid regions in México revealed that tactile stimulation of the cervix increased oxytocin levels and increased the milk released from the alveolar glands.

The Effects of The Oxytocin Hormone Induction on The Value of The Composition of Etawah Crossbred Goat Milk

H hormone oxytocin injection had a highly significant effect on increasing milk fat levels and significantly affected the decrease in milk density but did not affect the level of nonfat dry matter (BKTL), lactose and protein.

Role of hormones in persistency of lactation: A review

The objective of this review is to discuss the role of the hormones in lactation persistency so that it can be improved and higher production can be obtained.

Colorimetric Detection of Oxytocin in Bottle Gourd Using Cysteamine Functionalized Gold Nanoparticle (Cys-AuNPs)

A colorimetric method was devised for visual detection of oxytocin in bottle gourd using cysteamine-modified gold nanoparticles synthesized using conventional Turkevich method and showed good reliability in terms of selectivity, accuracy, and precision.

Theory-guided process evaluation of a multicomponent, technology-based 'SMART Eating' trial among Indian adults: an embedded mixed-methods study.

Process evaluation findings from the 'SMART Eating' intervention trial, which significantly improved fat, sugar and salt (FSS), and fruits and vegetables (FVs) intake among adults, are reported and contextual factors need to be considered while designing similar future interventions.

The oxytocin receptor system: structure, function, and regulation.

The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.

Oxytocin--its role in male reproduction and new potential therapeutic uses.

There is conclusive evidence that OT is synthesized within the mammalian testis, epididymis and prostate and the presence of OT receptors (OTRs) through the reproductive tract supports a local action for this peptide.

Oxytocin: a paracrine regulator of prostatic function.

It is hypothesized that oxytocin may act as a paracrine factor to regulate cell growth and that this may be secondary to its effects on the enzyme 5 alpha-reductase which converts testosterone to dihydrotestosterone.

Exogenous administration of oxytocin and its residual effects.

If at all oxytocin is secreted in the milk and is ingested alongwith milk, it is degraded by the gut enzymes and can not reach blood circulation in biologically active form, so there seems to be no harm in consuming milk from oxytocIn-treated dairy animals.

Oxytocin: a paracrine hormone in the regulation of parturition?

It is concluded that further clarification of this paracrine system within intrauterine tissues during late gestation could lead to more successful strategies for preventing or arresting preterm labour in women.

The neurohypophysis: recent developments.

  • A. G. Robinson
  • Biology, Medicine
    The Journal of laboratory and clinical medicine
  • 1987
The hormones of the neurohypophysis, vasopressin and oxytocin, have now been shown to be synthesized as part of a prohormone complex that includes a vasopressin-neurophysin and oxytocin-neurophysin,

Structure and expression of a human oxytocin receptor

The structure and expression of the human oxytocin receptor complementary DNA isolated by expression cloning are reported and it is concluded that the increase in receptor number in the myometrium at labour is, at least in part, due to the increased in mRNA.

Oxytocin and female sexuality.

More research is needed to clarify the role of oxytocin in human reproductive behaviors, including its potential 'aphrodisiac' or prosexual effect in women in the presence of the sex-steroid hormones.

Oxytocin is required for nursing but is not essential for parturition or reproductive behavior.

Oxytocin plays an essential role only in milk ejection in the mouse, and females lacking oxytocin have no obvious deficits in fertility or reproduction, including gestation and parturition.

Neurohypophysial hormones in the adrenal medulla.

  • V. AngJ. Jenkins
  • Biology, Medicine
    The Journal of clinical endocrinology and metabolism
  • 1984
It is postulated that the neurohypophysial peptides may have a regulatory function in the secretion of catecholamines.