Oxymetazoline hydrochloride cream for facial erythema associated with rosacea

  title={Oxymetazoline hydrochloride cream for facial erythema associated with rosacea},
  author={Nupur U. Patel and Shweta G. Shukla and Jessica Zaki and Steven R. Feldman},
  journal={Expert Review of Clinical Pharmacology},
  pages={1049 - 1054}
ABSTRACT Introduction: Rosacea is a chronic skin condition characterized by transient and persistent erythema of the central face. The symptom of persistent erythema can be particularly frustrating for both patients and physicians as it is difficult to treat. Areas covered: Current treatment options for the treatment of rosacea include metronidazole, azelaic acid, sodium sulfacetamide-sulfur, and brimonidine. Until recently, brimonidine gel was the only option approved specifically for the… 
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Rosacea: Diagnosis and Treatment.
Treatment for rosacea starts with avoidance of triggers and use of mild cleansing agents and moisturizing regimens, as well as photoprotection with wide-brimmed hats and broad-spectrum sunscreens (minimum sun protection factor of 30).
Rosacea: a common, yet commonly overlooked, condition.
Family physicians should be able to identify and effectively treat the majority of patients with rosacea, and consultation with subspecialists may be required for the management of rhinophyma, ocular complications, or severe disease.
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A55-year-oldmanpresentedwitha longhistoryofETRrosacea manifesting with prolonged facial flushing provoked by multiple stimuli including heat, exercise, sun exposure, and the consumption of alcoholic
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It now seems clear that the role of antibiotics in patients with rosacea depends upon their anti-inflammatory rather than their antimicrobial properties, and practitioners have the opportunity to practice good antibiotic stewardship when treating the disease, particularly with systemic therapies.
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The selectivity, vasoconstrictive and anti-inflammatory properties of brimonidine are in agreement with the benefits observed with this compound in the treatment of facial erythema in rosacea.
Burden of Disease: The Psychosocial Impact of Rosacea on a Patient's Quality of Life.
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Patients with rosacea have higher incidences of embarrassment, social anxiety, depression, and decreased QoL compared with the rest of the population, and new options that target the facial erythema of roSacea may help mitigate the negative psychological impact.
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