Oxygenated lipid signaling in tumor-associated macrophages—focus on colon cancer

@article{Colby2018OxygenatedLS,
  title={Oxygenated lipid signaling in tumor-associated macrophages—focus on colon cancer},
  author={Jennifer K Colby and Jonathan Jaoude and Fuyao Liu and Imad Shureiqi},
  journal={Cancer and Metastasis Reviews},
  year={2018},
  volume={37},
  pages={289-315}
}
Polyunsaturated fatty acids (PUFAs) are enzymatically converted to a variety of bioactive products through insertion of molecular oxygen. PUFA-derived mediators can have either inflammatory or anti-inflammatory/pro-resolving properties, depending upon their specific structures. The relative harm or benefit of these mediators can also be tissue and context dependent. These mediators play important roles in maintaining homeostasis and their dysregulation is involved in pathogenesis of cancers… CONTINUE READING
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SHOWING 1-10 OF 347 REFERENCES

High-mobility group box 1 suppresses resolvin D1-induced phagocytosis via induction of resolvin D1-inactivating enzyme, 15-hydroxyprostaglandin dehydrogenase

Kang, G.-J, +5 authors H Byun
  • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease,
  • 2015
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL