Oxygenases involved in thymine and thymidine metabolism inNeurospora crassa

@article{Bankel1972OxygenasesII,
  title={Oxygenases involved in thymine and thymidine metabolism inNeurospora crassa},
  author={L. Bankel and E. Holme and G. Lindstedt and S. Lindstedt},
  journal={FEBS Letters},
  year={1972},
  volume={21}
}
A number of enzyme-catalyzed oxygenations have been disclosed during the last 15 yr but the reaction mechanisms are still incompletely understood. In the case of the 2-ketoglutarate-dependent oxygenations, available evidence indicates that a peroxide of 2-ketoglutarate and the substrate to be hydroxylated is a reaction intermediate [ 1,2] ; recent suggestions of a primary formation of a peracid from 2-ketoglutarate followed by attack on the substrate [3] have not been supported by experimental… Expand
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