Oxygenase in the Rat Kidney Regulation of Cyclooxygenase-and Cytochrome P 450-Derived Eicosanoids by Heme

@inproceedings{Botros2002OxygenaseIT,
  title={Oxygenase in the Rat Kidney Regulation of Cyclooxygenase-and Cytochrome P 450-Derived Eicosanoids by Heme},
  author={Fady T. Botros and Michal Laniado-Schwartzman and Nader G Abraham},
  year={2002}
}
Heme oxygenase enzymes (HO-1 and HO-2) catalyze the conversion of heme to biliverdin, free iron, and carbon monoxide (CO). Heme and products derived from its metabolism potentially influence renal function and blood pressure by affecting the expression and/or activity of hemeproteins, including cytochrome P450 (CYP4A) monooxygenases and cyclooxygenases (COX… CONTINUE READING