Oxygen toxicity.

@article{Lodato1990OxygenT,
  title={Oxygen toxicity.},
  author={Robert F Lodato},
  journal={Critical care clinics},
  year={1990},
  volume={6 3},
  pages={749-65}
}
The paradox of oxygen therapy is that it can be both life saving and life destroying. Considered as one of the most important drugs available to the clinician, its "dose," determined as the product of the oxygen concentration used and the duration of its use, must be titrated to avoid toxicity while still achieving adequate systemic oxygenation. 

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