Oxygen toxicity as a function of time and PO2.

@article{Arieli1994OxygenTA,
  title={Oxygen toxicity as a function of time and PO2.},
  author={Ran Arieli},
  journal={Journal of basic and clinical physiology and pharmacology},
  year={1994},
  volume={5 1},
  pages={67-87}
}
  • Ran Arieli
  • Published 1994 in
    Journal of basic and clinical physiology and…
The quantification of O2 toxicity as a function of exposure time (t) and PO2 has been based mainly on the empirical rectangular hyperbola. The non-linear response of the O2-damaged physiological variable (DMG) as a function of time at constant PO2 can be related to the dependence of dDMG/dt on the DMG. The kinetics of the O2-derived chemical species suggests a power relationship between the DMG and PO2 rather than a linear relationship. The combination of time and PO2 considerations suggests… CONTINUE READING

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