Oxygen solubility, rheology and hemodynamics of perfluorocarbon emulsion blood substitutes.

@article{Millard1994OxygenSR,
  title={Oxygen solubility, rheology and hemodynamics of perfluorocarbon emulsion blood substitutes.},
  author={Ronald Wesley Millard},
  journal={Artificial cells, blood substitutes, and immobilization biotechnology},
  year={1994},
  volume={22 2},
  pages={
          235-44
        }
}
Perfluorocarbon-based blood substitute emulsions have been under development for more than a quarter century. The first generation emulsions have provided confirmation that the physical principals of high gas solubility and low viscosity can effectively support organ and organism respiration and metabolism. Clinical trials led the US FDA in 1990 to be the first to approve a 20 w/v % perfluorocarbon emulsion for human use as coronary angioplasty adjuvant therapy. Hemodynamic responses to… CONTINUE READING
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Zerebrale Effekte von Perfluorcarbonen

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