Oxygen-sensitive guanylyl cyclases in insects and their potential roles in oxygen detection and in feeding behaviors.

Abstract

Responses to hypoxia and hyperoxia depend critically on the ability of the animal to detect changes in O2 levels. However, it has only been recently that an O2-sensing system has been identified in invertebrates. Evidence is accumulating that this molecular O2 sensor is, surprisingly, a class of soluble guanylyl cyclase (sGC) known as atypical sGCs. It has… (More)

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