Oxygen-responsive genetic circuits constructed in Synechocystis sp. PCC 6803.

  title={Oxygen-responsive genetic circuits constructed in Synechocystis sp. PCC 6803.},
  author={Cheryl M. Immethun and Kenneth M Ng and Drew M DeLorenzo and Ben Waldron-Feinstein and Ying-Chiang J. Lee and Tae Seok Moon},
  journal={Biotechnology and bioengineering},
  volume={113 2},
As photoautotrophic prokaryotes, cyanobacteria are promising platforms for producing value-added bioproducts. However, few regulatory genetic parts and devices (e.g., inducible promoters and regulatory circuits) have been developed for these potential hosts. Furthermore, the devices that have been created respond only to a single input. To address these issues, we developed an inducible genetic circuit that generates heterologous proteins in response to oxygen, an environmental signal. To test… CONTINUE READING
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