Oxygen plasma surface modification enhances immobilization of simvastatin acid.

@article{Yoshinari2006OxygenPS,
  title={Oxygen plasma surface modification enhances immobilization of simvastatin acid.},
  author={Masao Yoshinari and Tohru Hayakawa and Kenichi Matsuzaka and Takashi Inoue and Yutaka Oda and Masaki Shimono and Takaharu Ide and Teruo Tanaka},
  journal={Biomedical research},
  year={2006},
  volume={27 1},
  pages={29-36}
}
Simvastatin acid (SVA) has been reported to stimulate bone formation with increased expression of BMP-2. Therefore, immobilization of SVA onto dental implants is expected to promote osteogenesis at the bone tissue/implant interface. The aim of this study was to evaluate the immobilization behavior of SVA onto titanium (Ti), O(2)-plasma treated titanium (Ti + O(2)), thin-film coatings of hexamethyldisiloxane (HMDSO), and O(2)-plasma treated HMDSO (HMDSO + O(2)) by using the quartz crystal… CONTINUE READING
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