Oxygen free radicals in acute pancreatitis of the rat.

  title={Oxygen free radicals in acute pancreatitis of the rat.},
  author={Mark H. Schoenberg and Michael B{\"u}chler and Margarida Gaspar and A Stinner and M. R. Younes and Ingo Melzner and Bernhard B{\"u}ltmann and Hans G{\"u}nther Beger},
  volume={31 10},
This study aimed to assess the role of oxygen free radicals in acute pancreatitis. Acute pancreatitis was induced in rats by infusion of the CCK-analogue cerulein (5 micrograms/kg per hour) for 30 minutes, 3.5 hours, and 12 hours. After the infusion, serum enzymes and conjugated tissue dienes and malondialdehyde were measured and tissue samples were subjected to electron and light microscopy. Electron microscopy after 30 minutes showed moderate intracellular alterations. After 3.5 hours of… CONTINUE READING


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Lipid peroxidation products in the pancreatic tissue of patients with acute pancreatitis

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