Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin.

@article{Abreu2000OxygenDI,
  title={Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin.},
  author={Isabel A Abreu and Lı́gia M. Saraiva and Jo{\~a}o N Carita and Harald Huber and K. O. Stetter and Diane E. Cabelli and Miguel Teixeira},
  journal={Molecular microbiology},
  year={2000},
  volume={38 2},
  pages={322-34}
}
Archaeoglobus fulgidus is a hyperthermophilic sulphate-reducing archaeon. It has an optimum growth temperature of 83 degrees C and is described as a strict anaerobe. Its genome lacks any homologue of canonical superoxide (O2.-) dismutases. In this work, we show that neelaredoxin (Nlr) is the main O2.- scavenger in A. fulgidus, by studying both the wild-type and recombinant proteins. Nlr is a 125-amino-acid blue-coloured protein containing a single iron atom/molecule, which in the oxidized state… CONTINUE READING