Oxygen-derived species: their relation to human disease and environmental stress.

@article{Halliwell1994OxygenderivedST,
  title={Oxygen-derived species: their relation to human disease and environmental stress.},
  author={Barry Halliwell and Carroll E. Cross},
  journal={Environmental Health Perspectives},
  year={1994},
  volume={102},
  pages={5 - 12}
}
Free radicals and other reactive oxygen species (ROS) are constantly formed in the human body, often for useful metabolic purposes. Antioxidant defenses protect against them, but these defenses are not completely adequate, and systems that repair damage by ROS are also necessary. Mild oxidative stress often induces antioxidant defense enzymes, but severe stress can cause oxidative damage to lipids, proteins, and DNA within cells, leading to such events as DNA strand breakage and disruption of… CONTINUE READING
Highly Influential
This paper has highly influenced 18 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 197 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 79 references

Aruoma 01, eds. DNA and Free Radicals

  • B Halliwell
  • 1993
Highly Influential
13 Excerpts

Free Radicals in Biology and Medicine, 2nd ed

  • B Halliwell, Gutteridge JMC
  • 1989
Highly Influential
17 Excerpts

The Chemical Basis of Radiation Biology

  • C. von Sonntag
  • London:Taylor and Francis,
  • 1987
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…