Oxygen cost of twitch and tetanic isometric contractions of rat skeletal muscle.

@article{Hood1986OxygenCO,
  title={Oxygen cost of twitch and tetanic isometric contractions of rat skeletal muscle.},
  author={David A. Hood and J. Cristopher Gorski and Ronald L. Terjung},
  journal={The American journal of physiology},
  year={1986},
  volume={250 4 Pt 1},
  pages={E449-56}
}
The distal muscles of a rat single hindlimb preparation, perfused at 14-15 ml/min, were stimulated sequentially for 10-min intervals at 12, 24, 36, 48, 60, 75, and 120 twitch/min (8 V, 0.05 ms) or at 7.5, 15, 30, 45, 60, 75, and 90 tetani/min (100-ms train, 100 Hz). Oxygen consumption (VO2) of the whole muscle increased up to 6- and 10-fold over rest during twitch and tetanic conditions, respectively. Tension development during each stimulation interval decreased sequentially at the higher… CONTINUE READING