Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling.

@article{Radk2013OxygenCA,
  title={Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling.},
  author={Zsolt Rad{\'a}k and Zhongfu Zhao and Erika Koltai and Hideki Ohno and Mustafa Atalay},
  journal={Antioxidants & redox signaling},
  year={2013},
  volume={18 10},
  pages={1208-46}
}
The complexity of human DNA has been affected by aerobic metabolism, including endurance exercise and oxygen toxicity. Aerobic endurance exercise could play an important role in the evolution of Homo sapiens, and oxygen was not important just for survival, but it was crucial to redox-mediated adaptation. The metabolic challenge during physical exercise results in an elevated generation of reactive oxygen species (ROS) that are important modulators of muscle contraction, antioxidant protection… CONTINUE READING
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