Oxygen consumption and ROS production are increased at the time of fertilization and cell cleavage in bovine zygotes.

@article{Lopes2010OxygenCA,
  title={Oxygen consumption and ROS production are increased at the time of fertilization and cell cleavage in bovine zygotes.},
  author={Ana Maria Souza Lopes and Michelle T Lane and Jeremy G. Thompson},
  journal={Human reproduction},
  year={2010},
  volume={25 11},
  pages={
          2762-73
        }
}
BACKGROUND Oxygen consumption is a key indicator of metabolic activity within embryos. Increased oxidative activity and REDOX changes at the time of fertilization have been suggested to signal Ca(2+) oscillations after sperm penetration. The objective of the present study was to determine the oxygen consumption and the REDOX status of zygotes and early embryos at the time of sperm penetration and cell cleavage and to investigate how metabolism relates to key temporal events and developmental… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 34 CITATIONS

Protective Effects of Quercetin Against Cadmium Chloride-Induced Oxidative Injury in Goat Sperm and Zygotes

  • Biological Trace Element Research
  • 2018
VIEW 11 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Peroxiredoxin as a functional endogenous antioxidant enzyme in pronuclei of mouse zygotes

  • The Journal of reproduction and development
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 56 REFERENCES

Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surrounding

P Guérin, S El Mouatassim, Y. Ménézo
  • Hum Reprod Update 2001;7:175–189
  • 2001
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Peaks of respiration and ROS production coincide with the time of fertilization and cell cleavage in bovine oocytes

AS Lopes, GC Dalvit, M Lane, JG Thompson
  • Hum Reprod
  • 2008
VIEW 1 EXCERPT

Peaks of respiration

Reprod, AS 22558–566.Lopes, GC Dalvit, M Lane, JG Thompson
  • 2007

The role of oxygen in ruminant preimplantation embryo development and metabolism

AJ Harvey
  • Anim Reprod Sci 2007;98:113–128
  • 2007
VIEW 1 EXCERPT