Oxygen concentration gradient across the ovarian follicular epithelium: model, predictions and implications.

@article{Gosden1986OxygenCG,
  title={Oxygen concentration gradient across the ovarian follicular epithelium: model, predictions and implications.},
  author={Roger G. Gosden and J. G. B. Byatt-Smith},
  journal={Human reproduction},
  year={1986},
  volume={1 2},
  pages={65-8}
}
A mathematical model has been devised for predicting the oxygen concentration gradient across the epithelium of ovarian follicles at pre-antral stages. Most dissolved oxygen entering the follicle by diffusion is evidently consumed in the outer layer of cells; little reaches the oocyte. Even when the rate of consumption or the diffusion coefficient of oxygen was adjusted by an order of magnitude to favour oxygen penetration, the concentration gradient into the follicle remained steep. On the… CONTINUE READING

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