Oxygen and renal hemodynamics in the conscious rat.

  title={Oxygen and renal hemodynamics in the conscious rat.},
  author={Bert Flemming and Erdmann Seeliger and Thomas Wronski and Keith Steer and Norman Arenz and Pontus Persson},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={11 1},
Previous studies have suggested a link between renal metabolism and local kidney hemodynamics to prevent potential hypoxic injury of particularly vulnerable nephron segments, such as the outer medullary region. The present study used three different inspiratory oxygen concentrations to modify renal metabolic state in the conscious rat (hypoxia 10% O2, normoxia 20% 02, and hyperoxia 100% 02). Renal blood flow (RBF) was assessed by ultrasound transit time; renal perfusion pressure (RPP) was… CONTINUE READING
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