Oxygen and carotid body chemotransduction: the cholinergic hypothesis - a brief history and new evaluation.

@article{Fitzgerald2000OxygenAC,
  title={Oxygen and carotid body chemotransduction: the cholinergic hypothesis - a brief history and new evaluation.},
  author={Robert S. Fitzgerald},
  journal={Respiration physiology},
  year={2000},
  volume={120 2},
  pages={89-104}
}
Oxygen can be said to be the most fundamentally necessary substrate for life. In those organisms having a cardiopulmonary system for delivering it in blood to the tissues the carotid body functions as the principal detector of decreases in arterial oxygen. Such a decrease stimulates an increase in neural output from the carotid body to the nucleus tractus solitarii, and this can precipitate a wide array of systemic reflex responses. The neural mechanisms involved in the genesis of increased… CONTINUE READING

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