Oxygen Transfer Characteristics of Miniaturized Bioreactor Systems

@inproceedings{Kirk2013OxygenTC,
  title={Oxygen Transfer Characteristics of Miniaturized Bioreactor Systems},
  author={Timothy V Kirk and Nicolas Szita},
  booktitle={Biotechnology and bioengineering},
  year={2013}
}
Since their introduction in 2001 miniaturized bioreactor systems have made great advances in function and performance. In this article the dissolved oxygen (DO) transfer performance of submilliliter microbioreactors, and 1-10 mL minibioreactors was examined. Microbioreactors have reached k(L) a values of 460 h(-1) , and are offering instrumentation and some functionality comparable to production systems, but at high throughput screening volumes. Minibioreactors, aside from one 1,440 h(-1) k(L… CONTINUE READING
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