Oxygen 18 investigation of the prostaglandin synthetase-dependent co-oxidation of diphenylisobenzofuran.

@article{Marnett1979Oxygen1I,
  title={Oxygen 18 investigation of the prostaglandin synthetase-dependent co-oxidation of diphenylisobenzofuran.},
  author={Lawrence J Marnett and Michael J. Bienkowski and W R Pagels},
  journal={The Journal of biological chemistry},
  year={1979},
  volume={254 12},
  pages={5077-82}
}
The mechanism of the prostaglandin synthetase-dependent co-oxidation of diphenylisobenzofuran has been investigated using arachidonic acid, 15-hydroperoxy-9a,lla-peroxido-5-cis-13-trans-prostadienoic acid (PGG& and 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid as substrates. Kinetic data establish that the arachidonic acid-dependent co-oxidation is… CONTINUE READING