Oxygen: from the benefits of inducing VEGF expression to managing the risk of hyperbaric stress.

@article{Patel2005OxygenFT,
  title={Oxygen: from the benefits of inducing VEGF expression to managing the risk of hyperbaric stress.},
  author={Viren Patel and Indira V. Chivukula and Sashwati Roy and Savita Khanna and Guanglong He and Navdeep Ojha and Amita Mehrotra and Lisa M Dias and Thomas K. Hunt and C. Sen},
  journal={Antioxidants \& redox signaling},
  year={2005},
  volume={7 9-10},
  pages={
          1377-87
        }
}
Hypoxia limits wound healing. Both normobaric (1 atm) and hyperbaric oxygen (HBO) approaches have been used clinically to oxygenate wound tissue. Recently, we reported that HBO ameliorates stress-induced impairment of dermal healing. We examined the effect of pressure on oxygen-induced vascular endothelial growth factor (VEGF) expression by human HaCaT keratinocytes. Next, we investigated the effect of HBO on whole-body redox and on the ratio of oxidized to reduced glutathione (GSSG/GSH) in the… 

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