Oxiracetam pharmacokinetics following single and multiple dose administration in the elderly

@article{Perucca2010OxiracetamPF,
  title={Oxiracetam pharmacokinetics following single and multiple dose administration in the elderly},
  author={E. Perucca and J. Parini and A. Albrici and M. Visconti and E. Ferrero},
  journal={European Journal of Drug Metabolism and Pharmacokinetics},
  year={2010},
  volume={12},
  pages={145-148}
}
SummaryThe kinetics of the nootropic drug oxiracetam was studied in 6 elderly female patients (age range 69–96 years) in good physical condition. After a single oral dose (800 mg), serum oxiracetam levels reached a peak (25 ± 6 ug/ml) within 1–3 h and declined thereafter with a half-life of 3 to 6 h. Eighty-four percent of the administered dose was recovered in urine as unchanged drug within 24 h. During a maintenance regimen (800 b.i.d. at 8 a.m. and 2 p.m.) for 7 days oxiracetam did not show… Expand
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