Oxindolealanine in age-related human cataracts.

  title={Oxindolealanine in age-related human cataracts.},
  author={Lilia A Rousseva and Elizabeth R Gaillard and David Paik and John C. Merriam and Victor Ryzhov and Donita L. Garland and James P. Dillon},
  journal={Experimental eye research},
  volume={85 6},
The present study was performed in order to obtain structural and quantitative information regarding the modifications that take place in the human lens as a result of tryptophan oxidation. In particular, the early tryptophan oxidation product, oxindolealanine (OIA) has been detected in lyophilized and hydrolyzed cataractous lenses by mass spectrometry. OIA… CONTINUE READING