Oxidized low-density lipoprotein induces differentiation of RAW264.7 murine macrophage cell line into dendritic-like cells.

@article{Shen2008OxidizedLL,
  title={Oxidized low-density lipoprotein induces differentiation of RAW264.7 murine macrophage cell line into dendritic-like cells.},
  author={Ling-Hong Shen and Lei Zhou and Bin-yao Wang and Jun Pu and Liu-hua Hu and Dajun Chai and Li Wang and Jin-zhang Zeng and Ben He},
  journal={Atherosclerosis},
  year={2008},
  volume={199 2},
  pages={257-64}
}
Dendtritic cells (DCs) are potent antigen-presenting cells and have an important role in the pathogenesis of atherosclerosis. Recent data suggests oxidized low-density lipoprotein (oxLDL) promotes the transition of a differentiating monocyte to a mature dendritic cell. In this study, we examined whether oxLDL could induce the differentiation of mature macrophages into DCs. After 48 h treatment with oxLDL, RAW264.7 cells increased in cell size and exhibited dendritic morphology. At the optimal… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Expression profiles of microRNAs in oxidized low-density lipoprotein-stimulated RAW 264.7 cells

In Vitro Cellular & Developmental Biology - Animal • 2017
View 2 Excerpts
Highly Influenced

MicroRNA-155 induces differentiation of RAW264.7 cells into dendritic-like cells.

International journal of clinical and experimental pathology • 2015
View 2 Excerpts

Kruppel-like factor 2 regulates dendritic cell activation in patients with acute coronary syndrome.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2013

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Inflammation, atherosclerosis, and coronary artery disease.

The New England journal of medicine • 2005
View 1 Excerpt

Similar Papers

Loading similar papers…