Oxidized cholesterol modulates age-related change in lipid metabolism in rats

  title={Oxidized cholesterol modulates age-related change in lipid metabolism in rats},
  author={Kyoichi Osada and Takehiro Kodama and Satoshi Noda and Koji Yamada and Michihiro Sugano},
For three weeks, male Sprague-Dawley rats at either four weeks (young) or eight months (adult) of age were pairfed one of the purified diets free of or containing either 0.2% of oxidized cholesterol mixture (cholesterol oxidation products) or 0.2% of cholesterol. Although the food intake was similar, dietary oxidized cholesterol lowered body weight gain in young rats, but did not increase relative liver weight, in contrast to the enlargement seen with dietary cholesterol. Oxidized cholesterol… CONTINUE READING
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