Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits.

@article{Staprans1998OxidizedCI,
  title={Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits.},
  author={Ilona Staprans and Xian Mang Pan and Joseph H. Rapp and Kennenth R Feingold},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1998},
  volume={18 6},
  pages={977-83}
}
Oxidized lipoproteins may play a role in atherosclerosis. Recently, we have demonstrated that the levels of oxidized fatty acids in the circulation correlate directly with the quantity of oxidized fatty acids in the diet and that dietary oxidized fatty acids accelerate atherosclerosis in rabbits. The present study tests the hypothesis that oxidized cholesterol in the diet accelerates the development of atherosclerosis. Rabbits were fed a diet containing 0.33% nonoxidized cholesterol (control… CONTINUE READING