Oxidized PLs and Vascular Inflammation

  title={Oxidized PLs and Vascular Inflammation},
  author={Maceler Aldrovandi and Valerie B. O’Donnell},
  booktitle={Current atherosclerosis reports},
Oxidized PLs (OxPLs) generated in health and disease are now recognized as important mediators of cellular signalling. There is an increasing body of evidence showing that PL peroxidation is not only increased in vascular disorders, but is also a physiological event of relevance to coagulation, innate immunity, and self-tolerance. Nonenzymatically formed OxPLs generated during chronic inflammation is an uncontrolled event, generating hundreds of diverse structures, and prone to more deleterious… CONTINUE READING

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