Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction.

@article{Tatsuguchi2003OxidizedLR,
  title={Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction.},
  author={Mariko Tatsuguchi and Michiko Furutani and Jun-ichi Hinagata and Toshiyuki Tanaka and Yoshiyuki Furutani and Shin-ichiro Imamura and Masatoshi Kawana and Tomoh Masaki and Hiroshi Kasanuki and Tatsuya Sawamura and Rumiko Matsuoka},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={303 1},
  pages={
          247-50
        }
}
Lectin-like oxidized low-density lipoprotein receptor (LOX-1/OLR1) has been suggested to play a role in the progression of atherogenesis. We analyzed the OLR1 gene and found a single nucleotide polymorphism (SNP), G501C, in patients with ischemic heart disease from a single family, which resulted in the missense mutation of K167N in LOX-1 protein. We compared the group of patients with myocardial infarction (MI) (n=102) with a group of clinically healthy subjects (n=102), and found that the MI… CONTINUE READING
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