Oxidized LDL increases and interferon-gamma decreases expression of CD36 in human monocyte-derived macrophages.

@article{Nakagawa1998OxidizedLI,
  title={Oxidized LDL increases and interferon-gamma decreases expression of CD36 in human monocyte-derived macrophages.},
  author={Takemasa Nakagawa and Shuichi Nozaki and Makoto Nishida and Janabi Mohamed Yakub and Yoshiaki Tomiyama and Atsuyuki Nakata and Kengo Matsumoto and Tohru Funahashi and Kaoru Kameda-Takemura and Yoshiyuki Kurata and Shizuya Yamashita and Yuji Matsuzawa},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1998},
  volume={18 8},
  pages={1350-7}
}
CD36 is a glycoprotein with an Mr of 88 kDa that is expressed on platelets, monocytes/macrophages, capillary endothelial cells, and adipocytes. We previously demonstrated that CD36 is involved in the uptake of oxidized low density lipoprotein (OxLDL) by using CD36-deficient macrophages (J Clin Invest. 1995;96:1859). However, the regulation of CD36 expression in human monocyte-derived macrophages has not been fully elucidated. The current study attempted to clarify the effect of OxLDL and… CONTINUE READING
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