Oxidized LDL immune complexes and coronary artery calcification in type 1 diabetes.

@article{LopesVirella2011OxidizedLI,
  title={Oxidized LDL immune complexes and coronary artery calcification in type 1 diabetes.},
  author={Maria F. Lopes-Virella and Nathaniel L Baker and Kelly J Hunt and John M Lachin and David Matthew Nathan and Gabriel Virella},
  journal={Atherosclerosis},
  year={2011},
  volume={214 2},
  pages={462-7}
}
OBJECTIVE Oxidized LDL (oxLDL) and oxLDL antibodies form immune complexes (IC) that reflect essential components in the development of atherosclerosis: dyslipidemia, oxidative stress and induction of a pro-inflammatory humoral immune response. We measured oxLDL in IC (oxLDL-IC) isolated from patients with type 1 diabetes to assess the relationship between oxLDL-IC and coronary artery calcification (CAC). METHODS OxLDL was measured in IC isolated from baseline samples from a subgroup of 476… CONTINUE READING