Oxidized LDL and thickness of carotid intima-media are associated with coronary atherosclerosis in middle-aged men: lower levels of oxidized LDL with statin therapy.

@article{Vasankari2001OxidizedLA,
  title={Oxidized LDL and thickness of carotid intima-media are associated with coronary atherosclerosis in middle-aged men: lower levels of oxidized LDL with statin therapy.},
  author={Tommi Juhani Vasankari and Markku O. Ahotupa and Jyri O. Toikka and Jura Mikkola and Kerttu Irjala and Pentti A. Pasanen and Kari Neuvonen and Olli T. Raitakari and Jorma Viikari},
  journal={Atherosclerosis},
  year={2001},
  volume={155 2},
  pages={403-12}
}
We investigated the relation between serum lipids including oxidized LDL and the severity of coronary atherosclerosis. Serum lipids and oxidized LDL was measured in 62 men (33-66 years), who underwent diagnostic coronary angiography and sonography to measure the carotid intima-media thickness. LDL oxidation was found in chemical analyses to be due to conjugated fatty acids in cholesteryl esters and triglycerides. Regression analysis indicated that the carotid intima-media thickness and the… CONTINUE READING

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