Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations.

@article{Limbach2005OxideNU,
  title={Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations.},
  author={Ludwig K Limbach and Yuchun Li and Robert N. Grass and Tobias Josef Brunner and Marcel A Hintermann and Martin Michael Muller and Detlef Gunther and Wendelin J Stark},
  journal={Environmental science & technology},
  year={2005},
  volume={39 23},
  pages={9370-6}
}
Quantitative studies on the uptake of nanoparticles into biological systems should consider simultaneous agglomeration, sedimentation, and diffusion at physiologically relevant concentrations to assess the corresponding risks of nanomaterials to human health. In this paper, the transport and uptake of industrially important cerium oxide nanoparticles, into human lung fibroblasts is measured in vitro after exposing thoroughly characterized particle suspensions to a fibroblast cell culture for… CONTINUE READING
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