Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-Walled Carbon Nanotubes

@inproceedings{Folkmann2009OxidativelyDD,
  title={Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-Walled Carbon Nanotubes},
  author={Janne Kj{\ae}rsgaard Folkmann and Lotte Risom and Nicklas Raun Jacobsen and H{\aa}kan Wallin and Steffen Loft and Peter M\oller},
  booktitle={Environmental health perspectives},
  year={2009}
}
BACKGROUND C60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to be used in medicine and consumer products with potential human exposure. The hazardous effects of these particles are expected to involve oxidative stress with generation of oxidatively damaged DNA that might be the initiating event in the development of cancer. OBJECTIVE In this study we investigated the effect of a single oral administration of C60 fullerenes and SWCNT. METHODS We measured the level of… CONTINUE READING

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