Oxidative tissue: perilipin 5 links storage with the furnace

  title={Oxidative tissue: perilipin 5 links storage with the furnace},
  author={Hong Wang and Carole Sztalryd},
  journal={Trends in Endocrinology & Metabolism},
Cellular energy homeostasis is a crucial function of oxidative tissues and is altered in obesity, a continuously rising health problem. Lipid droplets (LD) are thought to play a central role in lipid homeostasis by mediating the transient storage of fatty acids in the form of triglyceride, while preventing high levels of toxic lipid intermediates or oxidized lipids that mediate cellular lipotoxicity. Members of the perilipin protein family coating LD surfaces have been found to serve important… CONTINUE READING

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