Oxidative stress-related biomarkers in autism: systematic review and meta-analyses.

  title={Oxidative stress-related biomarkers in autism: systematic review and meta-analyses.},
  author={Alessandra Frustaci and Monica Neri and Alfredo Cesario and James B Adams and Enrico Domenici and Bernardo dalla Bernardina and Stefano Bonassi},
  journal={Free radical biology & medicine},
  volume={52 10},
Autism spectrum disorders (ASDs) are rarely diagnosed in children younger than 2 years, because diagnosis is based entirely on behavioral tests. Oxidative damage may play a central role in this pathogenesis, together with the interconnected transmethylation cycle and transsulfuration pathway. In an attempt to clarify and quantify the relationship between oxidative stress-related blood biomarkers and ASDs, a systematic literature review was carried out. For each identified study, mean biomarker… CONTINUE READING
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